Sono stati scelti gli ufficiali di gara che scenderanno in campo nelle partite del martedì di Champions League, dove Napoli e Inter saranno di scena rispettivamente contro Salisburgo e Borussia Dortmund. Per la gara del Signal Iduna Park, è stato selezionato l'olandese Makkelie, mentre sarà il polacco Marciniak a fischiare nell'incontro del San Paolo. Impegnati anche gli arbitri italiani: Rocchi dirigerà l'incontro tra Chelsea e Ajax; i suoi assistenti saranno Meli e Peretti, Mariani il quarto uomo, mentre i VAR saranno Valeri e Carbone. Assistenti in video italiani anche in Liverpool - Genk: si tratta di Irrati e Guida.
18:55 CET - Barcelona (Camp Nou)
FC Barcelona (ESP) - SK Slavia Praha (CZE) | Group F
Referee: Michael Oliver (ENG)
Assistant Referee 1: Stuart Burt (ENG)
Assistant Referee 2: Simon Bennett (ENG)
Fourth Official: Andrew Madley (ENG)
Video Assistant Referee: Christopher Kavanagh (ENG)
Assistant Video Assistant Referee: Lee Betts (ENG)
18:55 CET - St Petersburg (Gazprom Arena)
FC Zenit (RUS) - RB Leipzig (GER) | Group G
Referee: Orel Grinfeld (ISR)
Assistant Referee 1: Roi Hasan (ISR)
Assistant Referee 2: Idan Yarkoni (ISR)
Fourth Official: Eitan Shmuelevitz (ISR)
Video Assistant Referee: João Pedro da Silva Pinheiro (POR)
Assistant Video Assistant Referee: Roi Reinshreiber (ISR)
21:00 CET - Liverpool (Anfield)
Liverpool FC (ENG) - KRC Genk (BEL) | Group E
Referee: Ivan Kružliak (SVK)
Assistant Referee 1: Tomáš Somoláni (SVK)
Assistant Referee 2: Branislav Hancko (SVK)
Fourth Official: Filip Glova (SVK)
Video Assistant Referee: Massimiliano Irrati (ITA)
Assistant Video Assistant Referee: Marco Guida (ITA)
21:00 CET - Naples (Stadio San Paolo)
SSC Napoli (ITA) - FC Red Bull Salzburg (AUT) | Group E
Referee: Szymon Marciniak (POL)
Assistant Referee 1: Paweł Sokolnicki (POL)
Assistant Referee 2: Tomasz Listkiewicz (POL)
Fourth Official: Tomasz Musiał (POL)
Video Assistant Referee: Paweł Gil (POL)
Assistant Video Assistant Referee: Marcin Borkowski (POL)
21:00 CET - Dortmund (Signal-Iduna-Park)
Borussia Dortmund (GER) - FC Internazionale Milano (ITA) | Group F
Referee: Danny Makkelie (NED)
Assistant Referee 1: Mario Diks (NED)
Assistant Referee 2: Hessel Steegstra (NED)
Fourth Official: Kevin Blom (NED)
Video Assistant Referee: Jochem Kamphuis (NED)
Assistant Video Assistant Referee: Bas Nijhuis (NED)
21:00 CET - Décines-Charpieu (Groupama Stadium)
Olympique Lyonnais (FRA) - SL Benfica (POR) | Group G
Referee: Björn Kuipers (NED)
Assistant Referee 1: Sander van Roekel (NED)
Assistant Referee 2: Erwin Zeinstra (NED)
Fourth Official: Serdar Gözübüyük (NED)
Video Assistant Referee: Pol van Boekel (NED)
Assistant Video Assistant Referee: Joost van Zuilen (NED)
21:00 CET - València (Mestalla, camp del València)
Valencia CF (ESP) - Lille OSC (FRA) | Group H
Referee: Sergey Karasyov (RUS)
Assistant Referee 1: Igor Demeshko (RUS)
Assistant Referee 2: Maksim Gavrilin (RUS)
Fourth Official: Sergey Ivanov (RUS)
Video Assistant Referee: Bastian Dankert (GER)
Assistant Video Assistant Referee: Vitaliy Meshkov (RUS)
21:00 CET - London (Stamford Bridge)
Chelsea FC (ENG) - AFC Ajax (NED) | Group H
Referee: Gianluca Rocchi (ITA)
Assistant Referee 1: Filippo Meli (ITA)
Assistant Referee 2: Giorgio Peretti (ITA)
Fourth Official: Maurizio Mariani (ITA)
Video Assistant Referee: Paolo Valeri (ITA)
Assistant Video Assistant Referee: Ciro Carbone (ITA)